Pedals that stack with the Mesa/Boogie Studio Preamp

pushes an already-dirty tonePushes an already-dirty tone harder and tightens it up. (high gain → mid-forward)

Feed a high gain signal into Electro-Harmonix Green Russian Big Muff and it comes out closer to mid-forward

Goes in front of the amp

pushes an already-dirty tonePushes an already-dirty tone harder and tightens it up. (high gain → mid-forward)

Nobels ODR-1 pushes a high gain tone toward mid-forward

Goes in front of the amp

clean platform takes the driveA clean, high-headroom stage takes on dirt it can't generate by itself. (transparent → medium gain)

The transparent tone has headroom to spare — Klon KTR leans it toward medium gain to fill it in

Goes in front of the amp

sits in the right chain slotPlaced for where it does its job cleanly in the chain, not for a tonal interaction with the anchor.

Run Valco Black Hole Vintage Phaser after Mesa/Boogie Studio Preamp in the signal chain, clear of Mesa/Boogie Studio Preamp's own gain stage

Goes in front of the amp

shapes the dynamic responseShapes how the tone responds to picking dynamics rather than its frequency or gain.

DSM & Humboldt ClearComp Compressor's own compressed character is the real reason this is worth trying

Goes in front of the amp

sits in the right chain slotPlaced for where it does its job cleanly in the chain, not for a tonal interaction with the anchor.

Keep Mesa/Boogie Studio Preamp's high gain voice out front: Keeley Magnetic Echo goes in Mesa/Boogie Studio Preamp's effects loop so its modulated voice doesn't muddy it — goes in the amp's FX loop (or last, into a clean amp)

Sits in the amp's effects loop

sits in the right chain slotPlaced for where it does its job cleanly in the chain, not for a tonal interaction with the anchor.

Keep Mesa/Boogie Studio Preamp's high gain voice out front: Fender Hammertone Reverb goes in Mesa/Boogie Studio Preamp's effects loop so its lush voice doesn't muddy it — goes in the amp's FX loop (or last, into a clean amp)

Sits in the amp's effects loop